AlphaRet Overnight Cream

Experience the transformative power of the #1 dermatologist-recommended retinoid brand.*

AlphaRet Overnight Cream is a clinically validated prescription-strength retinoid that fights lines while it hydrates skin for visible results in 4 weeks.** Tested even on retinoid-sensitive users to be suitable for nightly use. ***

Why You'll Love It: Helps improve the appearance of fine lines and wrinkles, refines the look of uneven skin tone and texture, and improves skin hydration and visible redness.

All skinbetter science products are dermatologist tested, non-comedogenic, paraben free, fragrance free, dye free, and cruelty free.

*Among non-prescription brands sold by physicians or medical practices, in addition to other outlets or retailers. Blinded nationwide survey of dermatologists 2025. Responding dermatologists may have sales relationships with one or more medical aesthetic brands.

**A 12-week, split-face, randomized, dermatologist-led clinical study in participants with mild-to-severe photoaging (N=48) vs 0.025% tretinoin

***A 12-week multicenter, dermatologist-led clinical study evaluated nightly use of AlphaRet Overnight Cream in participants with self-identified retinoid sensitivity and mild-to-moderate photoaging. (N=56)

Benefits

This 20x award-winning retinoid is powered by patented AlphaRet technology and a blend of skin rejuvenating ingredients like peptides, antioxidants, and ceramides to improve the appearance of fine lines and wrinkles while simultaneously reducing visible redness and boosting hydration. See visible results in the look of wrinkles and uneven skin tone in as little as 4 weeks. **

• #1 dermatologist-recommended retinoid brand.*
• Visible results in 4 weeks.**
• 33% improvement in the appearance of fine lines and wrinkles in 12 weeks.**
• 14% improvement in hydration in 12 weeks.**
• 98% of retinoid-sensitive users agree that AlphaRet can be used nightly.***
• Patented AlphaRet Technology combines a retinoid and an alpha hydroxy acid (AHA) in a novel molecule for effective, tolerable overnight skin rejuvenation.
• Features a targeted peptide blend and antioxidant complex to promote elasticity and help neutralize free radicals.

*Among non-prescription brands sold by physicians or medical practices, in addition to other outlets or retailers. Blinded nationwide survey of dermatologists 2025. Responding dermatologists may have sales relationships with one or more medical aesthetic brands.

**A 12-week, split-face, randomized, dermatologist-led clinical study in participants with mild-to-severe photoaging (N=48) vs 0.025% tretinoin

***A 12-week multicenter, dermatologist-led clinical study evaluated nightly use of AlphaRet Overnight Cream in participants with self-identified retinoid sensitivity and mild-to-moderate photoaging. (N=56)

How to Use

Use as part of your evening skincare regime after cleansing.

Apply a thin layer of AlphaRet to a clean, dry face. Apply evenly all over the face, avoiding the eye area. Follow with other skinbetter science products in your evening regimen.

Protect with sunbetter sunscreen during the day for additional skincare benefits and daily sun protection.

Review recommended order of product application.

Sunburn Alert: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards. Caution: This product contains retinoid in a topical form. If you are pregnant, lactating or planning to become pregnant, consult a physician before use. If using more than one exfoliating product, irritation may occur.

Ingredients

KEY INGREDIENTS

• AlphaRet: A unique combination of a retinoid and an AHA (lactic acid).
• Glycolic Acid: Helps retexturize and enhances performance of AlphaRet.
• Targeted Peptide Blend: Helps smooth the appearance of wrinkles, skin firmness and resiliency.
• Ultra Hydrating Blend of Ceramides, Squalane, Niacinamide and Hyaluronic Acid: Helps to counteract dryness, providing hydration and moisture.
• Allantoin Glycyrrhetinic Acid, Bisabolol, and Green Tea Extract: Ingredients with calming properties that also help reduce the appearance of redness.
• Vitamins C & E and CoEnzyme Q10: Provide antioxidant protection.

FULL INGREDIENT LIST

Aqua/Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891)